Parkinson’s Disease Prediction Using Convolutional Neural Networks and Hand-Drawn Image Analysis

Authors

  • Uche-Jerry Nzenwata Department of Computer Science, Babcock University, Nigeria
  • Ayodeji G. Abiodun Department of Computer Science, Babcock University, Nigeria
  • Adelola Olayinka Department of Computer Science, Babcock University, Nigeria
  • Oluwabamise J. Adeniyi Department of Computer Science, Babcock University, Nigeria
  • Akwaronwu B. Gazie Department of Computer Science, Babcock University, Nigeria

DOI:

https://doi.org/10.70112/ajcst-2024.13.2.4270

Keywords:

Parkinson’s Disease (PD), Neurodegenerative Disorder, Neural Convolutional Network (CNN), Feature Extraction, Classification Accuracy

Abstract

Parkinson’s Disease (PD) is a serious neurodegenerative disorder, with over 10 million cases globally in 2020, significantly affecting patients’ quality of life. The progression of the disease has been statistically proven, underscoring the importance of early diagnosis. As many as 80% of those diagnosed with PD begin to experience spinal degeneration, leading to other impairments and disabilities within approximately 10 years. Moreover, up to 35% of patients require assistance to walk or perform daily living activities within 5 years of diagnosis. The proposed study employs a neural convolutional network (CNN) to predict PD using 64x64 pixel hand-drawn images from 244 PD patients and 228 healthy individuals. K-nearest neighbors (KNN)-based feature extraction was applied as a data pre-processing method before feeding the data into the CNN layers. Model training involved tuning hyper parameters and testing several learning rates, ranging from 0.1 to 0.00001. The highest learning rate of 0.001 yielded the best performance, achieving classification accuracies, precision, sensitivity, and F1 score of 97.93%, 92%, 80%, and 86%, respectively, with a 5% increase in performance accuracy. These results demonstrate the model’s effective ability to discriminate between healthy individuals and PD patients based on hand-drawn samples.

References

N. Boualoulou, M. Miyara, B. Nsiri, and T. Belhoussine Drissi, “A novel Parkinson’s disease detection algorithm combined EMD, BFCC, and SVM classifier,” Diagnostyka, vol. 24, no. 4, pp. 1-10, Oct. 2023,doi: 10.29354/diag/171712.

S. Latif et al., “Dopamine in Parkinson’s disease,” Clin. Chim. Acta,vol. 522, pp. 114-126, Nov. 2021, doi: 10.1016/j.cca.2021.08.009.

E. I. Abdukodirov, K. M. Khalimova, and R. J. Matmurodov,“Hereditary-genealogical features of Parkinson’s disease and theirearly detection of the disease,” Int. J. Health Sci. (Qassim), Apr. 2022, doi: 10.53730/ijhs.v6nS1.5802.

S. S, A. S, G. V. V. Rao, P. V, K. Mohanraj, and R. Azhagumurugan, “Parkinson’s disease prediction using machine learning algorithm,” in2022 International Conference on Power, Energy, Control andTransmission Systems (ICPECTS), IEEE, Dec. 2022, pp. 1-5, doi: 10.1109/ICPECTS56089.2022.10047447.

L. di Biase et al., “Gait analysis in Parkinson’s disease: An overview of the most accurate markers for diagnosis and symptoms monitoring,” Sensors, vol. 20, no. 12, p. 3529, Jun. 2020, doi: 10.3390/s20123529.

D. Palacios-Alonso, G. Melendez-Morales, A. Lopez-Arribas, C.Lazaro-Carrascosa, A. Gomez-Rodellar, and P. Gomez-Vilda, “MonParLoc: A speech-based system for Parkinson’s disease analysis and monitoring,” IEEE Access, vol. 8, pp. 188243-188255, 2020, doi: 10.1109/ACCESS.2020.3031646.

M. Olson, T. E. Lockhart, and A. Lieberman, “Motor learning deficitsin Parkinson’s disease (PD) and their effect on training response in gait and balance: A narrative review,” Front. Neurol., vol. 10, Feb. 2019,doi: 10.3389/fneur.2019.00062.

Y. Kumar, A. Koul, R. Singla, and M. F. Ijaz, “Artificial intelligencein disease diagnosis: A systematic literature review, synthesizing framework and future research agenda,” J. Ambient Intell. Humaniz.Comput., vol. 14, no. 7, pp. 8459-8486, Jul. 2023, doi: 10.1007/s12 652-021-03612-z.

P. N. Srinivasu, N. Sandhya, R. H. Jhaveri, and R. Raut, “From blackbox to explainable AI in healthcare: Existing tools and case studies,” Mob. Inf. Syst., vol. 2022, pp. 1-20, Jun. 2022, doi: 10.1155/ 2022/8167821.

M. Alissa et al., “Parkinson’s disease diagnosis using convolutional neural networks and figure-copying tasks,” Neural Comput. Appl.,vol. 34, no. 2, pp. 1433-1453, Jan. 2022, doi: 10.1007/s00521-021-06469-7.

Y. Zhang and Y. Ma, “Application of supervised machine learning algorithms in the classification of sagittal gait patterns of cerebral palsy children with spastic diplegia,” Comput. Biol. Med., vol. 106, pp. 33-39, Mar. 2019, doi: 10.1016/j.compbiomed.2019.01.009.

S. M. A. Asaduzzaman Sakib, A. F. M. Nazmus Shusmita, and S. A.Kabir, “Detection of Parkinson’s disease from neuro-imagery using deep neural network with transfer learning,” BRAC University, 2020.[Online]. Available: https://dspace.bracu.ac.bd/xmlui/handle/10361/ 14457.

J. T. J. Goschenhofer, F. M. J. Pfister, K. A. Yuksel, B. Bischl, and U.Fietzek, “Wearable-based Parkinson’s disease severity monitoring using deep learning,” 2019. [Online]. Available: https://ecmlpkdd2019.org/downloads/paper/575.pdf.

M. B. Makarious et al., “Multi-modality machine learning predicting Parkinson’s disease,” npj Park. Dis., vol. 8, no. 1, p. 35, Apr. 2022, doi: 10.1038/s41531-022-00288-w.

N. Khoury, F. Attal, Y. Amirat, L. Oukhellou, and S. Mohammed, “Data-driven based approach to aid Parkinson’s disease diagnosis,” Sensors, vol. 19, no. 2, p. 242, Jan. 2019, doi: 10.3390/s19020242.

A. Al Imran, A. Rahman, H. Kabir, and S. Rahim, “The impact of feature selection techniques on the performance of predicting Parkinson’s disease,” Int. J. Inf. Technol. Comput. Sci., vol. 10, no. 11, pp. 14-29, Nov. 2018, doi: 10.5815/ijitcs.2018.11.02.

K.-M. Giannakopoulou, I. Roussaki, and K. Demestichas, “Internet of Things technologies and machine learning methods for Parkinson’s disease diagnosis, monitoring and management: A systematic review,”Sensors, vol. 22, no. 5, p. 1799, Feb. 2022, doi: 10.3390/s22051799.

P. Arora, A. Mishra, and A. Malhi, “Diagnosis of Parkinson’s disease genes using LSTM and MLP-based multi-feature extraction methods,” Int. J. Data Min. Bioinform., vol. 27, no. 4, pp. 326-348, 2023,doi: 10.1504/IJDMB.2023.134301.

L. Ali, C. Zhu, N. A. Golilarz, A. Javeed, M. Zhou, and Y. Liu,“Reliable Parkinson’s disease detection by analyzing handwritten drawings: Construction of an unbiased cascaded learning system based on feature selection and adaptive boosting model,” IEEE Access,vol. 7, pp. 116480-116489, 2019, doi: 10.1109/ACCESS.2019.2932037.

S. Chakraborty, S. Aich, J. S. Sim, E. Han, J. Park, and H. C. Kim,“Parkinson’s disease detection from spiral and wave drawings using convolutional neural networks: A multistage classifier approach,” in 2020 22nd International Conference on Advanced Communication Technology (ICACT), IEEE, Feb. 2020, pp. 298-303, doi: 10.23919/ ICACT48636.2020.9061497.

P. Zham, D. K. Kumar, P. Dabnichki, S. P. Arjunan, and S. Raghav,“Distinguishing different stages of Parkinson’s disease using composite index of speed and pen-pressure of sketching a spiral,” Front. Neurol., vol. 8, Sep. 2017, doi: 10.3389/fneur.2017.00435.

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Published

30-09-2024

How to Cite

Nzenwata, U.-J., Abiodun, A. G., Olayinka, A., Adeniyi, O. J., & Gazie, A. B. (2024). Parkinson’s Disease Prediction Using Convolutional Neural Networks and Hand-Drawn Image Analysis. Asian Journal of Computer Science and Technology, 13(2), 1–13. https://doi.org/10.70112/ajcst-2024.13.2.4270